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Vaccine acceptance rises to 99% in Sargodha after microbe literacy drive, study reveals

Islamabad: A government-backed trial in Sargodha has recorded a dramatic improvement in community health behaviour, with vaccine uptake jumping to 99 percent and handwashing practices rising by 38 percent after households were taught to observe live germs and microorganisms through microscopes, a technique health experts say could transform disease prevention at the grassroots level.

According to the findings of the Cluster Randomized Control Trial conducted by Development Synergies International (DSI) in collaboration with the Ministry of Health and NUST, the Microbe Literacy Initiative (MLI) led to sharp improvements in vaccine confidence, hygiene behaviour, sanitation practices and trust in health workers.

Mothers who attended microbe sessions were significantly more likely to complete their children’s immunisation course, while polio vaccine coverage in intervention areas rose to 99 percent compared to 81.8 percent in control zones, narrowing drop-out rates and strengthening herd protection.

Researchers said the intervention which was carried out through Lady Health Workers at household level also raised awareness of disease transmission and reduced misconceptions linking illness to water quality alone. The microbe learning model, where women directly visualised germs from household water, soil and food particles under microscopes, triggered what experts described as a “behavioural shift based on scientific evidence, not slogans.”

Health Minister of State Dr Mukhtar Ahmed Bharath, who addressed the dissemination event at the National Science and Technology Park, said the Sargodha trial proved that preventive awareness, if rooted in science and delivered through trusted community channels, can reduce disease burden more effectively than expensive treatment plans.

He said a large number of parliamentarians and even senior journalists still believe diseases like hepatitis B and C come from dirty water alone, which reflects how poor health literacy is even among educated segments.

“If our lawmakers and media practitioners lack basic understanding, how can we expect rural communities to make informed choices? Prevention begins when people know what a microbe is and how infection actually spreads,” Dr Bharath said, stressing that primary healthcare cannot succeed without public understanding of microbes, hygiene and rational antibiotic use.

The minister said integrating microbe literacy into the Pakistan Pandemic Preparedness Fund and primary healthcare system would strengthen resilience against both biological threats and climate-driven health emergencies. He said Pakistan cannot afford a repeat of COVID-era confusion when misinformation and weak community trust cost lives and slowed vaccine acceptance.

DSI Chief Executive and RCT Lead Investigator Dr Muhammad Tariq said the study confirmed that microbe literacy is not just health education—it is a tool of community empowerment and national preparedness. He said households that saw microbes with their own eyes were far more likely to boil water, wash hands, avoid unnecessary antibiotics and comply with vaccination schedules.

“Once a mother observes a living organism moving in a water droplet taken from her own container, she does not need a lecture to understand infection. That single visual moment changes behaviour more than any poster,” he told the audience, calling for linkage of the initiative with EPI outreach, nutrition programmes and AMR stewardship plans.

Other speakers, including Prof Tahir Khadim, Dr Nisar Ahmed Cheema, Dr Aslam Asad and Amer Sheikh, said the success of the Sargodha pilot shows how low-cost scientific engagement can help Pakistan meet its One Health, SDG and pandemic security targets. They said community knowledge is the missing link in most health campaigns, where infrastructure exists but public understanding lags.

Experts called for expanding the microbe literacy model to more districts, train Lady Health Workers in live demonstration techniques, and embed microbial awareness in school and mother support group programmes. Participants said empowering communities with direct scientific experience is the only sustainable way to cut preventable infections, reduce antibiotic misuse and break the cycle of intergenerational malnutrition and disease.

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